Conditional CRISPR-Cas Genome Editing in Drosophila to Generate Intestinal Tumors
CRISPR-Cas has revolutionized genetics and extensive efforts have been made to enhance its editing efficiency by developing increasingly more elaborate tools.Here, we evaluate the CRISPR-Cas9 system in Drosophila melanogaster to assess its ability to induce stem cell-derived tumors in the intestine.We generated conditional tissue-specific CRISPR kn